Product Datasheet
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Product Description |
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Product: |
Cathepsin D, Human Liver |
Catalog Number: |
HCD |
Product Page: |
https://www.mol-innov.com/products/ |
Description: |
Cathepsin D is an estrogen-regulated protein associated with tissue breakdown. Levels of cathepsin D have been positively correlated with recurring breast cancers of both node-negative and node-positive types. Additionally cathepsin D has been associated with amyloid formation in Alzheimer's plaques. As cathepsin D activity is increased by cigarette smoke, the enzyme may contribute to lung tissue damage in smokers. Activity: >=300 units per mg protein. One unit is defined as the amount of enzyme that digests hemoglobin-releasing peptides which are soluble in 10percent TCA. The reaction is measured by an increase of an A 280 of 1.0 per 60 minutes at 37oC . Substrate: acid denatured hemoglobin, pH 1.8 (0.2percent in reaction mixture). Buffer: 100 mM formate, pH 3.3. Prepared from tissue shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE. Add deionized water to original volume, aliquot and freeze unused portion. |
Recommended Storage: |
SAMPLE |
Shipping Conditions: |
365 units/mg |
Minimum Shelf Life: |
232.75 |
Source: |
Lyophilized |
Molecular Weight: |
Proteins |
Extinction Coefficient: |
42,000 |
Antigen: |
-70 C |
Target: |
Lyophilized powder |
Target Molecular Weight: |
HUMAN PLASMA PROTEINS |
Host: |
565.25 |
Clonality: |
5 |
Isotype: |
Human liver |
Clone: |
s |
Applications: |
Cold pack |
Cross-reactivity: |
3 years from delivery |
Concentration: |
245 |
Volume: |
595 |
Titer: |
0.002M Sodium Phosphate; pH 6.5 |
Buffer: |
SAMPLE |
Form: |
0.025 mg |
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Optimal experimental conditions and working dilutions must be determined by the end user. Sample concentration and volume are for example purposes only and do not necessarily represent the product that will be received. Please contact us for a current lot-specific product datasheet. |
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For in vitro laboratory use only |
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Molecular Innovations, Inc. - 46430 Peary Court, Novi, MI 48377, USA Tel: (888) 557-5055 - Fax: (248) 896-0148 - info@mol-innov.com |