Product Datasheet

 
Product Description
 
Product: Human Factor IXa-beta
Catalog Number: HFIXA
Product Page: https://www.mol-innov.com/products/
Description: Human Factor IXa is prepared from Human Factor IX by activation with Bovine Factor XIa. This Bovine Factor XIa is removed after activation. Complete activation is observed by SDS-PAGE. The Factor XIa activates Factor IX in a two-step reaction. In the first step, an internal Arg-Ala bond is cleaved, and in the second step, an Arg-Val bond is cleaved. The second cleavage leads to the liberation of an activation peptide from the NH2-terminal portion of the heavy chain to produce Factor IXa-beta. Factor IXa-alpha has only the second cleavage at the Arg-Val bond with about half the coagulant activity of Human Factor IXa-beta. Complete activation is observed by SDS-PAGE. This protein purity is determined by SDS-PAGE and shows total reduction upon incubation with 2-mercaptoethanol. Thaw rapidly in a 37C water bath without allowing protein to warm to 37C and immediately cool on ice.
Recommended Storage: SAMPLE
Minimum Shelf Life: 418.00
Source: 5.0 mg/ml
Molecular Weight: Proteins
Extinction Coefficient: 45,000
Antigen: -70 C
Target: Frozen liquid
Target Molecular Weight: FACTOR IX
Host: 1349
Clonality: 5
Isotype: Human plasma
Clone: s
Applications: Dry ice
Cross-reactivity: 3 years from delivery
Concentration: 440
Volume: 1420
Titer: 0.02M MES; 0.6M NaCl; pH 6.0
Buffer: SAMPLE
Form: 0.5 mg
Preservative: 0.1 ml
 
Optimal experimental conditions and working dilutions must be determined by the end user. Sample concentration and volume are for example purposes only and do not necessarily represent the product that will be received. Please contact us for a current lot-specific product datasheet.
 
For in vitro laboratory use only
 
Molecular Innovations, Inc. - 46430 Peary Court, Novi, MI 48377, USA
Tel: (888) 557-5055 - Fax: (248) 896-0148 - info@mol-innov.com