Product Datasheet

 
Product Description
 
Product: GC Globulin, Human Plasma, Mixed Type
Catalog Number: HGCG
Product Page: https://www.mol-innov.com/products/
Description: GC globulin, also known as Vitamin D-binding protein (DBP/VDB), Vitamin D-binding protein-macrophage activating factor (DBP-MAF), and Gc protein-derived macrophage activating factor (Gc-MAF), is an alpha 2 glycoprotein composed of a single polypeptide chain and present in plasma at levels of 20-55 mg/100 ml. It functions in the binding and transport of vitamin D and may also play an important role in actin homeostatis since it has been shown to bind monomeric actin with high affinity. GC-globulin also binds membranes of both circulating B and T lymphocytes. Clinically, concentrations are reduced in patients with severe liver diseases. GC-globulin may also play an important role in the mechanism of the osteomalacia that occurs with Itai-Itai disease. Prepared from plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE. Add deionized water to original volume, aliquot and freeze unused portion.
Recommended Storage: SAMPLE
Minimum Shelf Life: 232.75
Source: Lyophilized
Molecular Weight: Proteins
Extinction Coefficient: 56,000
Antigen: -70 C
Target: Lyophilized powder
Target Molecular Weight: HUMAN PLASMA PROTEINS
Host: 460.75
Clonality: 5
Isotype: Human plasma
Clone: s
Applications: Cold pack
Cross-reactivity: 3 years from delivery
Concentration: 245
Volume: 485
Titer: 0.02M Sodium Phosphate; 0.15M NaCl; pH 7.4
Buffer: SAMPLE
Form: 1.0 mg
 
Optimal experimental conditions and working dilutions must be determined by the end user. Sample concentration and volume are for example purposes only and do not necessarily represent the product that will be received. Please contact us for a current lot-specific product datasheet.
 
For in vitro laboratory use only
 
Molecular Innovations, Inc. - 46430 Peary Court, Novi, MI 48377, USA
Tel: (888) 557-5055 - Fax: (248) 896-0148 - info@mol-innov.com