Product Datasheet
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| Product Description |
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| Product: |
Kallikrein, Human Plasma |
| Catalog Number: |
HPKA |
| Product Page: |
https://www.mol-innov.com/products/IHUKLK1MG |
| Description: |
Activation of Prekallikrein with Factor alpha-XIIa produces the enzymatically active Kallikrein. Kallikrein is a serine protease which consists of a heavy chain (Mr 52kD) and light chains (Mr either 36 or 33 kD) linked by disulfide bridges. Kallikrein possesses enzymatic activity toward Factor XII, HK, Plasminogen, Factors XI, IX, and VII, prorenin and the complement system. After activation, the activating enzyme Factor XIIa is removed by affinity chromatography. Human Kallikrein purity is >95percent by SDS-PAGE and shows complete reduction upon incubation with 2-mercaptoethanol. Prepared from plasma found negative by FDA accepted methods for Anti-HIV1/2, Anti-HTLV I & II, HBsAg, Anti-HCV, Syphilis, HBC Ab, HIV-1 p24 Ag or HIV-1 RNA, HCV RNA and HBV RNA. Donors are screened for CJD (Creutzfeldt-Jakob Disease). |
| Recommended Storage: |
SAMPLE |
| Minimum Shelf Life: |
484.50 |
| Source: |
2.0 mg/ml |
| Molecular Weight: |
Proteins |
| Extinction Coefficient: |
86,000 - 88,000 |
| Antigen: |
-70 C |
| Target: |
Frozen liquid |
| Target Molecular Weight: |
KALLIKREIN/PREKALLIKREIN |
| Host: |
2270.5 |
| Clonality: |
5 |
| Isotype: |
Human plasma |
| Clone: |
s |
| Applications: |
Dry ice |
| Cross-reactivity: |
3 years from delivery |
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| Sample Characteristics |
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| Lot Number: |
HPKA-IHUKLK5MG |
| Aliquot: |
1 x Human Kallikrein Purified 5mg |
| Concentration: |
510 |
| Volume: |
2390 |
| Titer: |
0.004M Sodium Acetate; 0.15M NaCl; pH 5.3 |
| Buffer: |
SAMPLE |
| Form: |
1.0 mg |
| Preservative: |
0.5 ml |
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| Optimal experimental conditions and working dilutions must be determined by the end user. Sample concentration and volume are for example purposes only and do not necessarily represent the product that will be received. Please contact us for a current lot-specific product datasheet. |
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| For in vitro laboratory use only |
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Molecular Innovations, Inc. - 46430 Peary Court, Novi, MI 48377, USA
Tel: (888) 557-5055 - Fax: (248) 896-0148 - info@mol-innov.com |