Product Datasheet
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Product Description |
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Product: |
Ac-TVASSSTA Octapeptide |
Catalog Number: |
PEP-1 |
Product Page: |
https://www.mol-innov.com/products/ICMACOLY5MG |
Description: |
Ac-TVASSSTA is an Octapeptide mimic of the N-terminal residues of the reactive center loop of PAI-1 (cf. P14-P7 residues). The Octapeptide inactivates PAI-1 by substituting for strand 4 in beta-sheet A in a manner that competes with formation of the latent species. Insertion of the peptide into beta-sheet A effectively forms a stable complex that converts PAI-1 into a substrate for tissue-type plasminogen activator (tPA) and other target proteinases. The resulting species of PAI-1 is thermodynamically stable and is useful for investigating the role of reactive center loop insertion. Supplied as a lyophilized powder. Add deionized water to original volume, aliquot and freeze unused portion. |
Recommended Storage: |
SAMPLE |
Minimum Shelf Life: |
350.00 |
Source: |
Lyophilized |
Molecular Weight: |
Proteins |
Extinction Coefficient: |
765 |
Antigen: |
-70 C |
Target: |
Lyophilized powder |
Target Molecular Weight: |
PAI-1 |
Host: |
598.5 |
Clonality: |
30 |
Isotype: |
Chemical |
Applications: |
Cold pack |
Cross-reactivity: |
3 years from delivery |
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Sample Characteristics |
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Lot Number: |
PEP-1-ICMACOLY10MG |
Aliquot: |
1 x Chemically-Derived Ac-TVASSSTA Octapeptide Purified Lyophilized 10mg |
Concentration: |
500 |
Volume: |
855 |
Titer: |
0.1M HEPES; 0.1M NaCl; pH 7.4 |
Buffer: |
SAMPLE |
Form: |
5 mg |
Preservative: |
0.5 ml before lyophilization |
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Optimal experimental conditions and working dilutions must be determined by the end user. Sample concentration and volume are for example purposes only and do not necessarily represent the product that will be received. Please contact us for a current lot-specific product datasheet. |
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For in vitro laboratory use only |
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Molecular Innovations, Inc. - 46430 Peary Court, Novi, MI 48377, USA Tel: (888) 557-5055 - Fax: (248) 896-0148 - info@mol-innov.com |