Heparin Cofactor II is a single chain glycoprotein prepared from fresh frozen human plasma. HCII is a specific inhibitor of thrombin with increased activity in the presence of heparin. Heparin Cofactor II purity is determined by SDS-PAGE and the activity is measured by the ability to inhibit thrombin in the presence of saturating concentrations of heparin.
Gene Name: SERPIND1
Gene ID: 3053
Swiss-Prot/UniProt ID: P05546