This human immunoglobulin G antigen assay is intended for the quantitative determination of total human IgG antigen in serum, plasma, hybridoma cell supernatants, ascites or other biological fluids. The assay does not distinguish IgG subclasses. The Human IgG standard provided in this kit is now calibrated against the WHO International Standard for Human Serum Immunoglobulins G, A and M (NIBSC Code 67/086).