The low molecular weight form of uPA is purified from auto-catalytic digestion of recombinant human urokinase produced in insect cells. LMW uPA contains the proteinase domain and is separated from the amino terminal fragment by cleavage at the Lys135-Lys136 bond. For plasminogen activation and receptor binding studies.
Gene Name: PLAU
Gene ID: 5328
Swiss-Prot/UniProt ID: P00749


Citations:
1. Lund, I.K. et al. (2008) J. Biol. Chem. 283: 32506-32515.