Human protein S is isolated from fresh frozen plasma by a combination of conventional methods and immunoaffinity chromatography. Protein S exists in two forms in human plasma, as the free protein and in complex with C4b-binding protein. This is the free protein from plasma which serves as a cofactor for the anticoagulant activity of activated protein C. Human protein S is a single-chain glycoprotein with >95percent purity as determined by SDS-PAGE.
Gene ID: 5627
Swiss-Prot/UniProt ID: P07225