Human tissue plasminogen activator, >85% single chain
Human tissue-type plasminogen activator (tPA) is a 527 amino acid glycoprotein. Synthesized from cDNA from a human melanoma cell line. It is recombinantly produced in Chinese Hamster Ovary (CHO) cells. Fully active, >85percent single chain.
Gene Name: PLAT Gene ID: 5327 Swiss-Prot/UniProt ID: P00750
Citations:
1. Sha, J. et al. ( 2009) J. Bacteriol. 191:3095-3107.