Mouse tPA with a double mutation that is permanently single chain and lacks catalytic activity. The non-catalytic mutation site is S481A on the mature protein and S510A on the complete mRNA sequence (UniProtKB: locus TPA_MOUSE, accession P11214). The non-cleavable mutation site is 279E on the mature protein and R308E on the complete mRNA sequence (UniProtKB: locus TPA_MOUSE, accession P11214). Recombinantly produced in insect cells.
Gene Name: PLAT
Gene ID: 18791
Swiss-Prot/UniProt ID: P11214