New Hypertension Products from
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Renin |
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Human Renin |
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Renin is an aspartyl protease that is specific for only one substrate, angiotensinogen. Molecular Innovations human renin is produced from the proenzyme prorenin by proteolytic cleavage of a 43 amino acid N-terminal prosegment using limited enzymatic digestion by trypsin. Conversion to active renin is >99.9%.
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Prorenin |
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Human Prorenin |
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Untagged Human Prorenin made in Human Embryonic Kidney cells.
Fully activatable to Renin by catalytic trypsin. Competitor's price: $500 for 0.1 mg Our price: $325 for 0.1 mg Click to order! |
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| Prorenin (C-terminal 8X-His tag) | |||
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Rat Prorenin 8x His (Expression in Human Embryonic Kidney cells) |
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Theoretical Ext. coefficient 280nm 0.1% (1 mg/ml) = 1.13 Number of amino acids = 381 + 8 His residues - Molecular weight 41,849 less glycosylation Theoretical pI= 5.31 – Purity >95% - fully activates to renin with catalytic trypsin. Click to order! |
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Mouse Prorenin 8x His (Expression in Human Embryonic Kidney cells) | ||
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Theoretical Ext. coefficient 280nm 0.1% (1 mg/ml) = 1.10 Number of amino acids = 380 + 8 His residues - Molecular weight 41,711 less glycosylation Theoretical pI= 5.87 – Purity >95% resistant to tryptic digestion as reported in the literature. Click to order! |
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Human Prorenin 8x His (Expression in Human Embryonic Kidney cells) | ||
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Theoretical Ext. coefficient 280nm 0.1% (1 mg/ml) = 1.09 Number of amino acids = 394 + 8 His residues - Molecular weight 43,725 less glycosylation Theoretical pI= 6.52 – Purity >98% - fully activates to renin with catalytic trypsin. Click to order! |
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Dog Prorenin 8x His (Expression in Human Embryonic Kidney cells) | ||
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Dog Renin 8x His (Expression in Human Embryonic Kidney cells) | ||
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Renin is an aspartyl protease that is specific for only one substrate, angiotensinogen. Molecular Innovations dog renin is produced from the proenzyme prorenin by proteolytic cleavage of a 43 amino acid N-terminal prosegment using limited enzymatic digestion by immobilized trypsin. Conversion to active renin is >98 percent.
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| Prorenin Antibodies | |||
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Monoclonal Antibodies to Human Prorenin (Clone 4B5-E3)
Inhibitory monoclonal antibodies directed to human Prorenin. Blocks proteolytic conversion of prorenin to renin by catalytic amounts of trypsin. This antibody recognizes and binds only to Prorenin. It does not bind or otherwise interact with active Renin. Suitable for: WB, ELISA. Click to order! |
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Polyclonal Antibodies to Human Renin Polyclonal antibodies (host sheep) to human renin. IgG fraction purified by immobilized Protein G. Click to order! |
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Polyclonal Antibodies to Mouse and Rat Prorenin/Renin Polyclonal antibodies (host sheep) to rat prorenin. Strongly cross reacts with mouse renin. IgG fraction purified by immobilized Protein G. Click to order! |
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Prorenin Kits |
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Human Prorenin ELISA Kits This human prorenin assay is intended for the quantitative determination of prorenin in biological fluids. Active renin will not be detected by this assay. Prorenin is measured directly by ELISA without pretreatment of samples or conversion to renin. We have validated this kit using pooled normal human plasma and serum. Results in 2 hours! Click to order! Rat Prorenin ELISA Kit The sensitive measurement of total rat prorenin and renin antigen is easily performed with this 96 well strip format ELISA kit. Rat prorenin and renin in plasma, serum, urine or cell culture media binds capture antibody coated onto a micro titer plate. Anti-rat prorenin primary antibody binds to the captured prorenin. Excess antibody is washed away, and bound antibody is then reacted with the secondary antibody. TMB substrate is used for color development at 450 nm. All reagents and standards are provided in these ELISA kits. Click to order! |
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Prorenin-depleted plasma |
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Human Renin/Prorenin double Depleted Plasma Prepared from frozen human plasma using immobilized anti-human Renin IgG. Click to order! |
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Coming Soon |
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Active Human, Mouse and Rat Renin |
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Native, Untagged Prorenin and Renin |
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Monoclonal Antibodies to Active Renin |
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Renin Activity ELISA Kit |
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